A conditional <i>Smg6</i> mutant mouse model reveals circadian clock regulation through the nonsense-mediated mRNA decay pathway.

Katsioudi, Georgia; Dreos, René; Arpa, Enes S; Gaspari, Sevasti; Liechti, Angelica; Sato, Miho; Gabriel, Christian H; Kramer, Achim; Brown, Steven A; Gatfield, David

A conditional Smg6 mutant mouse model reveals circadian clock regulation through the nonsense-mediated mRNA decay pathway.

Katsioudi, Georgia; Dreos, René; Arpa, Enes S; Gaspari, Sevasti; Liechti, Angelica; Sato, Miho; Gabriel, Christian H; Kramer, Achim; Brown, Steven A; Gatfield, David.

Afiliación

Katsioudi G; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Dreos R; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Arpa ES; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Gaspari S; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Liechti A; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Sato M; Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zürich, Zürich, Switzerland.
Gabriel CH; Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Laboratory of Chronobiology, Berlin, Germany.
Kramer A; Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Laboratory of Chronobiology, Berlin, Germany.
Brown SA; Chronobiology and Sleep Research Group, Institute of Pharmacology and Toxicology, University of Zürich, Zürich, Switzerland.
Gatfield D; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

Sci Adv ; 9(2): eade2828, 2023 01 13.

Article en En | MEDLINE | ID: mdl-36638184

Asunto(s)

Relojes Circadianos; Degradación de ARNm Mediada por Codón sin Sentido; Animales; Ratones; Relojes Circadianos/genética; Codón sin Sentido/genética; Procesamiento Postranscripcional del ARN; ARN Mensajero/genética; ARN Mensajero/metabolismo; Factores de Transcripción/metabolismo

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Relojes Circadianos / Degradación de ARNm Mediada por Codón sin Sentido Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Sci Adv Año: 2023 Tipo del documento: Article País de afiliación: Suiza

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