Cinnamaldehyde Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating TLR4/NF-&#954;B Signaling Pathway and NLRP3 Inflammasome Activation.

Tan, Xiaofen; Wen, Yifan; Han, Zhijun; Su, Xuyang; Peng, Jing; Chen, Feng; Wang, Yadong; Wang, Tianming; Wang, Changzhong; Ma, Kelong

Cinnamaldehyde Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Modulating TLR4/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation.

Tan, Xiaofen; Wen, Yifan; Han, Zhijun; Su, Xuyang; Peng, Jing; Chen, Feng; Wang, Yadong; Wang, Tianming; Wang, Changzhong; Ma, Kelong.

Afiliación

Tan X; College of Integrated Chinese and Western Medicine (College of Life Science), Anhui University of Chinese Medicine, Hefei, 230012, P.âR. China.
Wen Y; College of Integrated Chinese and Western Medicine (College of Life Science), Anhui University of Chinese Medicine, Hefei, 230012, P.âR. China.
Han Z; College of Integrated Chinese and Western Medicine (College of Life Science), Anhui University of Chinese Medicine, Hefei, 230012, P.âR. China.
Su X; College of Integrated Chinese and Western Medicine (College of Life Science), Anhui University of Chinese Medicine, Hefei, 230012, P.âR. China.
Peng J; College of Integrated Chinese and Western Medicine (College of Life Science), Anhui University of Chinese Medicine, Hefei, 230012, P.âR. China.
Chen F; College of Integrated Chinese and Western Medicine (College of Life Science), Anhui University of Chinese Medicine, Hefei, 230012, P.âR. China.
Wang Y; Institute of Integrated Chinese and Western Medicine, Anhui Academy of Chinese Medicine, Hefei, 230012, P.âR. China.
Wang T; College of Integrated Chinese and Western Medicine (College of Life Science), Anhui University of Chinese Medicine, Hefei, 230012, P.âR. China.
Wang C; Institute of Integrated Chinese and Western Medicine, Anhui Academy of Chinese Medicine, Hefei, 230012, P.âR. China.
Ma K; Key Laboratory of Xin'An Medicine, Ministry of Education, Anhui Academy of Chinese Medicine, Hefei, 230012, P.âR. China.

Chem Biodivers ; 20(2): e202200089, 2023 Feb.

Article en En | MEDLINE | ID: mdl-36653304

Asunto(s)

Colitis Ulcerosa; Colitis; Ratones; Animales; FN-kappa B/metabolismo; Inflamasomas; Factor de Transcripción ReIA/metabolismo; Proteína con Dominio Pirina 3 de la Familia NLR; Sulfato de Dextran; Inhibidor NF-kappaB alfa/metabolismo; Inhibidor NF-kappaB alfa/farmacología; Inhibidor NF-kappaB alfa/uso terapéutico; Proteínas NLR; Receptor Toll-Like 4/metabolismo; Receptor Toll-Like 4/uso terapéutico; Ciclooxigenasa 2/metabolismo; Simulación del Acoplamiento Molecular; Colitis/inducido químicamente; Transducción de Señal; Colitis Ulcerosa/tratamiento farmacológico; Inflamación; Modelos Animales de Enfermedad

Palabras clave

NLRP3 inflammasome; TLR4/NF-κB pathway; cinnamaldehyde; network pharmacology; ulcerative colitis

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Colitis Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Chem Biodivers Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2023 Tipo del documento: Article

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