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Mitochondrial creatine sensitivity is lost in the D2.mdx model of Duchenne muscular dystrophy and rescued by the mitochondrial-enhancing compound Olesoxime.
Bellissimo, Catherine A; Delfinis, Luca J; Hughes, Meghan C; Turnbull, Patrick C; Gandhi, Shivam; DiBenedetto, Sara N; Rahman, Fasih A; Tadi, Peyman; Amaral, Christina A; Dehghani, Ali; Cobley, James N; Quadrilatero, Joe; Schlattner, Uwe; Perry, Christopher G R.
Afiliación
  • Bellissimo CA; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.
  • Delfinis LJ; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.
  • Hughes MC; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.
  • Turnbull PC; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.
  • Gandhi S; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.
  • DiBenedetto SN; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.
  • Rahman FA; Faculty of Health, Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.
  • Tadi P; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.
  • Amaral CA; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.
  • Dehghani A; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.
  • Cobley JN; Redox Biology Group, Centre for Health Sciences, University of the Highlands and Islands, Inverness, United Kingdom.
  • Quadrilatero J; Faculty of Health, Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.
  • Schlattner U; Laboratory of Fundamental and Applied Bioenergetics, University Grenoble Alpes, Inserm U1055, Grenoble, France and Institut Universiatire de France Paris, France.
  • Perry CGR; School of Kinesiology & Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.
Am J Physiol Cell Physiol ; 324(5): C1141-C1157, 2023 05 01.
Article en En | MEDLINE | ID: mdl-36689672
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Distrofia Muscular de Duchenne Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Am J Physiol Cell Physiol Asunto de la revista: FISIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Distrofia Muscular de Duchenne Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Am J Physiol Cell Physiol Asunto de la revista: FISIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Canadá