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Lactate oxidase/vSIRPα conjugates efficiently consume tumor-produced lactates and locally produce tumor-necrotic H2O2 to suppress tumor growth.
Kang, Yujin; Yeo, Mirae; Choi, Hyukjun; Jun, Heejin; Eom, Soomin; Park, Seong Guk; Yoon, Haejin; Kim, Eunhee; Kang, Sebyung.
Afiliación
  • Kang Y; Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.
  • Yeo M; Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.
  • Choi H; Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.
  • Jun H; Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.
  • Eom S; Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.
  • Park SG; Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.
  • Yoon H; Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea.
  • Kim E; Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea. Electronic address: ehkim@unist.ac.kr.
  • Kang S; Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Republic of Korea. Electronic address: sabsab7@unist.ac.kr.
Int J Biol Macromol ; 231: 123577, 2023 Mar 15.
Article en En | MEDLINE | ID: mdl-36758763
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Peróxido de Hidrógeno / Neoplasias Límite: Animals Idioma: En Revista: Int J Biol Macromol Año: 2023 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Peróxido de Hidrógeno / Neoplasias Límite: Animals Idioma: En Revista: Int J Biol Macromol Año: 2023 Tipo del documento: Article