Identification of Small-Molecule Inhibitors of the Salmonella FraB Deglycase Using a Live-Cell Assay.

Sabag-Daigle, Anice; Boulanger, Erin F; Thirugnanasambantham, Pankajavalli; Law, Jamison D; Bogard, Alex J; Behrman, Edward J; Gopalan, Venkat; Ahmer, Brian M M

Sabag-Daigle, Anice; Boulanger, Erin F; Thirugnanasambantham, Pankajavalli; Law, Jamison D; Bogard, Alex J; Behrman, Edward J; Gopalan, Venkat; Ahmer, Brian M M.

Afiliación

Sabag-Daigle A; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA.
Boulanger EF; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA.
Thirugnanasambantham P; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, USA.
Law JD; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, USA.
Bogard AJ; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, USA.
Behrman EJ; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, USA.
Gopalan V; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, USA.
Ahmer BMM; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA.

Microbiol Spectr ; : e0460622, 2023 Feb 21.

Article en En | MEDLINE | ID: mdl-36809033

Palabras clave

FraB; Salmonella; antimicrobial agents; enzyme kinetics; high-throughput screen; sugar-phosphate toxicity

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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Diagnostic_studies Idioma: En Revista: Microbiol Spectr Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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