IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii.

Clark, Joseph T; Weizman, Orr-El; Aldridge, Daniel L; Shallberg, Lindsey A; Eberhard, Julia; Lanzar, Zachary; Wasche, Devon; Huck, John D; Zhou, Ting; Ring, Aaron M; Hunter, Christopher A

Clark, Joseph T; Weizman, Orr-El; Aldridge, Daniel L; Shallberg, Lindsey A; Eberhard, Julia; Lanzar, Zachary; Wasche, Devon; Huck, John D; Zhou, Ting; Ring, Aaron M; Hunter, Christopher A.

Afiliación

Clark JT; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.
Weizman OE; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA.
Aldridge DL; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.
Shallberg LA; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.
Eberhard J; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.
Lanzar Z; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.
Wasche D; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA.
Huck JD; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA.
Zhou T; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA.
Ring AM; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA. Electronic address: aaron.ring@yale.edu.
Hunter CA; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA. Electronic address: chunter@vet.upenn.edu.

Cell Rep ; 42(3): 112147, 2023 03 28.

Article en En | MEDLINE | ID: mdl-36827187

Asunto(s)

Toxoplasma; Toxoplasmosis Animal; Humanos; Animales; Interleucina-18/metabolismo; Células Asesinas Naturales; Interleucina-12/metabolismo; Inmunidad Innata

Palabras clave

CD4 T cells; CD8 T cell; CP: Immunology; CP: Microbiology; IFN-gamma; IL-18; IL-18 binding protein; NK cell; Toxoplasma; cytokine; infection; pathology

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Toxoplasma / Toxoplasmosis Animal Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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