Therapeutic Potential of an Azithromycin-Colistin Combination against XDR <i>K. pneumoniae</i> in a 3D Collagen-Based In Vitro Wound Model of a Biofilm Infection.

Moshynets, Olena V; Baranovskyi, Taras P; Iungin, Olga S; Krikunov, Alexey A; Potochilova, Viktoria V; Rudnieva, Kateryna L; Potters, Geert; Pokholenko, Ianina

Therapeutic Potential of an Azithromycin-Colistin Combination against XDR K. pneumoniae in a 3D Collagen-Based In Vitro Wound Model of a Biofilm Infection.

Moshynets, Olena V; Baranovskyi, Taras P; Iungin, Olga S; Krikunov, Alexey A; Potochilova, Viktoria V; Rudnieva, Kateryna L; Potters, Geert; Pokholenko, Ianina.

Afiliación

Moshynets OV; Biofilm Study Group, Department of Cell Regulatory Mechanisms, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Zabolotnoho Str. 150, 03680 Kyiv, Ukraine.
Baranovskyi TP; CeMM, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, A-1090 Vienna, Austria.
Iungin OS; Biofilm Study Group, Department of Cell Regulatory Mechanisms, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Zabolotnoho Str. 150, 03680 Kyiv, Ukraine.
Krikunov AA; Department of Biotechnology, Leather and Fur, Faculty of Chemical and Biopharmaceutical Technologies, Kyiv National University of Technologies and Design, Nemyrovycha-Danchenka Street 2, 01011 Kyiv, Ukraine.
Potochilova VV; National Amosov Institute of Cardio-Vascular Surgery Affiliated to National Academy of Medical Sciences of Ukraine, Amosov Str. 6, 02000 Kyiv, Ukraine.
Rudnieva KL; Kyiv City Maternity Hospital â 2, Mostytska 11, 02000 Kyiv, Ukraine.
Potters G; Kyiv Regional Clinical Hospital, Baggovutovskaya Str. 1, 04107 Kyiv, Ukraine.
Pokholenko I; Department of Microbiology, Virology and Immunology, Bogomolets National Medical University, Shevchenka Blvd. 13, 01601 Kyiv, Ukraine.

Antibiotics (Basel) ; 12(2)2023 Feb 01.

Article en En | MEDLINE | ID: mdl-36830203

Palabras clave

Klebsiella pneumonia; MDR/XDR/PDR Gram-negative infection; azithromycin; biofilms; colistin methanesulfonate; combined antibacterial therapy; wound model

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Antibiotics (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Ucrania

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Antibiotics (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Ucrania