Sniper2L is a high-fidelity Cas9 variant with high activity.

Kim, Young-Hoon; Kim, Nahye; Okafor, Ikenna; Choi, Sungchul; Min, Seonwoo; Lee, Joonsun; Bae, Seung-Min; Choi, Keunwoo; Choi, Janice; Harihar, Vinayak; Kim, Youngho; Kim, Jin-Soo; Kleinstiver, Benjamin P; Lee, Jungjoon K; Ha, Taekjip; Kim, Hyongbum Henry

Kim, Young-Hoon; Kim, Nahye; Okafor, Ikenna; Choi, Sungchul; Min, Seonwoo; Lee, Joonsun; Bae, Seung-Min; Choi, Keunwoo; Choi, Janice; Harihar, Vinayak; Kim, Youngho; Kim, Jin-Soo; Kleinstiver, Benjamin P; Lee, Jungjoon K; Ha, Taekjip; Kim, Hyongbum Henry.

Afiliación

Kim YH; Toolgen, Seoul, Republic of Korea.
Kim N; Department of Pharmacology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Okafor I; Graduate Program of Biomedical Engineering, Yonsei University College of Medicine, Seoul, Republic of Korea.
Choi S; Graduate Program of NanoScience and Technology, Yonsei University, Seoul, Republic of Korea.
Min S; Department of Pharmacology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Lee J; Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.
Bae SM; Department of Biology, Johns Hopkins University, Baltimore, MD, USA.
Choi K; Department of Pharmacology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Choi J; LG AI Research, Seoul, Republic of Korea.
Harihar V; Toolgen, Seoul, Republic of Korea.
Kim Y; Toolgen, Seoul, Republic of Korea.
Kim JS; Toolgen, Seoul, Republic of Korea.
Kleinstiver BP; Department of Biophysics, Johns Hopkins University, Baltimore, MD, USA.
Lee JK; Department of Biophysics, Johns Hopkins University, Baltimore, MD, USA.
Ha T; Toolgen, Seoul, Republic of Korea.
Kim HH; Department of Biochemistry and NUS Synthetic Biology for Clinical & Technological Innovation (SynCTI), National University of Singapore, Singapore, Singapore.

Nat Chem Biol ; 19(8): 972-980, 2023 08.

Article en En | MEDLINE | ID: mdl-36894722

Asunto(s)

Sistemas CRISPR-Cas; Edición Génica; ADN/genética

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sistemas CRISPR-Cas / Edición Génica Tipo de estudio: Prognostic_studies Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2023 Tipo del documento: Article

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