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Decrypting drug actions and protein modifications by dose- and time-resolved proteomics.
Zecha, Jana; Bayer, Florian P; Wiechmann, Svenja; Woortman, Julia; Berner, Nicola; Müller, Julian; Schneider, Annika; Kramer, Karl; Abril-Gil, Mar; Hopf, Thomas; Reichart, Leonie; Chen, Lin; Hansen, Fynn M; Lechner, Severin; Samaras, Patroklos; Eckert, Stephan; Lautenbacher, Ludwig; Reinecke, Maria; Hamood, Firas; Prokofeva, Polina; Vornholz, Larsen; Falcomatà, Chiara; Dorsch, Madeleine; Schröder, Ayla; Venhuizen, Anton; Wilhelm, Stephanie; Médard, Guillaume; Stoehr, Gabriele; Ruland, Jürgen; Grüner, Barbara M; Saur, Dieter; Buchner, Maike; Ruprecht, Benjamin; Hahne, Hannes; The, Matthew; Wilhelm, Mathias; Kuster, Bernhard.
Afiliación
  • Zecha J; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Bayer FP; German Cancer Consortium, Partner Site Munich, 80336 Munich, Germany.
  • Wiechmann S; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Woortman J; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Berner N; German Cancer Consortium, Partner Site Munich, 80336 Munich, Germany.
  • Müller J; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Schneider A; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Kramer K; German Cancer Consortium, Partner Site Munich, 80336 Munich, Germany.
  • Abril-Gil M; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Hopf T; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Reichart L; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Chen L; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
  • Hansen FM; OmicScouts GmbH, 85354 Freising, Germany.
  • Lechner S; OmicScouts GmbH, 85354 Freising, Germany.
  • Samaras P; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Eckert S; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Lautenbacher L; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Reinecke M; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Hamood F; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Prokofeva P; German Cancer Consortium, Partner Site Munich, 80336 Munich, Germany.
  • Vornholz L; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Falcomatà C; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Dorsch M; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Schröder A; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Venhuizen A; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
  • Wilhelm S; German Cancer Consortium, Partner Site Munich, 80336 Munich, Germany.
  • Médard G; Institute of Experimental Cancer Therapy, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 80336 Munich, Germany.
  • Stoehr G; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, 45147 Essen, Germany.
  • Ruland J; German Cancer Consortium (DKTK), Partner Site University Hospital Essen, 45147 Essen, Germany.
  • Grüner BM; OmicScouts GmbH, 85354 Freising, Germany.
  • Saur D; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Buchner M; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Ruprecht B; Proteomics and Bioanalytics, Department of Molecular Life Sciences, School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.
  • Hahne H; OmicScouts GmbH, 85354 Freising, Germany.
  • The M; German Cancer Consortium, Partner Site Munich, 80336 Munich, Germany.
  • Wilhelm M; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
  • Kuster B; German Center for Infection Research (DZIF), Partner Site Munich, 81675 Munich, Germany.
Science ; 380(6640): 93-101, 2023 04 07.
Article en En | MEDLINE | ID: mdl-36926954
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Procesamiento Proteico-Postraduccional / Apoptosis / Proteómica / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Science Año: 2023 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Procesamiento Proteico-Postraduccional / Apoptosis / Proteómica / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Science Año: 2023 Tipo del documento: Article País de afiliación: Alemania