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Entropic analysis of antigen-specific CDR3 domains identifies essential binding motifs shared by CDR3s with different antigen specificities.
Xu, Alexander M; Chour, William; DeLucia, Diana C; Su, Yapeng; Pavlovitch-Bedzyk, Ana Jimena; Ng, Rachel; Rasheed, Yusuf; Davis, Mark M; Lee, John K; Heath, James R.
Afiliación
  • Xu AM; Institute for Systems Biology, Seattle, WA 98109, USA; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Samuel Oschin Comprehensive Cancer Institute
  • Chour W; Institute for Systems Biology, Seattle, WA 98109, USA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Keck School of Medicine, University of Southern California, Los Angeles, CA 91125, USA.
  • DeLucia DC; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Su Y; Institute for Systems Biology, Seattle, WA 98109, USA; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Pavlovitch-Bedzyk AJ; Computational and Systems Immunology Program, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Ng R; Institute for Systems Biology, Seattle, WA 98109, USA.
  • Rasheed Y; Institute for Systems Biology, Seattle, WA 98109, USA.
  • Davis MM; Computational and Systems Immunology Program, Stanford University School of Medicine, Stanford, CA 94305, USA; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Microbiology and Immunology, Stanford University School
  • Lee JK; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA 98195, USA.
  • Heath JR; Institute for Systems Biology, Seattle, WA 98109, USA. Electronic address: jim.heath@isbscience.org.
Cell Syst ; 14(4): 273-284.e5, 2023 04 19.
Article en En | MEDLINE | ID: mdl-37001518
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T / Receptores de Antígenos de Linfocitos T alfa-beta Idioma: En Revista: Cell Syst Año: 2023 Tipo del documento: Article
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Receptores de Antígenos de Linfocitos T / Receptores de Antígenos de Linfocitos T alfa-beta Idioma: En Revista: Cell Syst Año: 2023 Tipo del documento: Article