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Immunity to pathogenic fungi in the eye.
Abbondante, Serena; Leal, Sixto M; Clark, Heather L; Ratitong, Bridget; Sun, Yan; Ma, Li-Jun; Pearlman, Eric.
Afiliación
  • Abbondante S; Department of Ophthalmology, and Department of Physiology and Biophysics, University of California, Irvine, CA, USA.
  • Leal SM; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Clark HL; University of Rochester Medical Center, Rochester NY, USA.
  • Ratitong B; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Sun Y; Department of Ophthalmic Research, Cole Eye Institute and Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
  • Ma LJ; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA.
  • Pearlman E; Department of Ophthalmology, and Department of Physiology and Biophysics, University of California, Irvine, CA, USA. Electronic address: eric.pearlman@uci.edu.
Semin Immunol ; 67: 101753, 2023 05.
Article en En | MEDLINE | ID: mdl-37060806
ABSTRACT
Fusarium, Aspergillus and Candida are important fungal pathogens that cause visual impairment and blindness in the USA and worldwide. This review will summarize the epidemiology and clinical features of corneal infections and discuss the immune and inflammatory responses that play an important role in clinical disease. In addition, we describe fungal virulence factors that are required for survival in infected corneas, and the activities of neutrophils in fungal killing, tissue damage and cytokine production.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fusarium / Queratitis Límite: Humans Idioma: En Revista: Semin Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fusarium / Queratitis Límite: Humans Idioma: En Revista: Semin Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos