Massively Parallel Double-Selection Workflow for the Evolution of Molecular Switches Based on Surface-Display in Escherichia coli.

Givelet, Louis; Bienau, Alexandra; Simmel, Friedrich C

Givelet, Louis; Bienau, Alexandra; Simmel, Friedrich C.

Afiliación

Givelet L; Technical University Munich, School of Natural Sciences, Department of Bioscience Chair of Physics of Synthetic Biological Systems, Am Coulombwall 4a, 85748, Garching, Germany.
Bienau A; Technical University Munich, School of Natural Sciences, Department of Bioscience Chair of Physics of Synthetic Biological Systems, Am Coulombwall 4a, 85748, Garching, Germany.
Simmel FC; Technical University Munich, School of Natural Sciences, Department of Bioscience Chair of Physics of Synthetic Biological Systems, Am Coulombwall 4a, 85748, Garching, Germany.

Chemistry ; 29(37): e202300845, 2023 Jul 03.

Article en En | MEDLINE | ID: mdl-37079773

Asunto(s)

Escherichia coli; Riboswitch; Escherichia coli/genética; Escherichia coli/metabolismo; Teofilina/metabolismo; Teofilina/farmacología; Ligandos; Flujo de Trabajo

Palabras clave

RNA; directed evolution; high-throughput screening; molecular switches; synthetic biology

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Escherichia coli / Riboswitch Idioma: En Revista: Chemistry Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Alemania

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