NSD1 deposits histone H3 lysine 36 dimethylation to pattern non-CG DNA methylation in neurons.

Hamagami, Nicole; Wu, Dennis Y; Clemens, Adam W; Nettles, Sabin A; Li, Aidan; Gabel, Harrison W

Hamagami, Nicole; Wu, Dennis Y; Clemens, Adam W; Nettles, Sabin A; Li, Aidan; Gabel, Harrison W.

Afiliación

Hamagami N; Department of Neuroscience, Washington University School of Medicine, St Louis, MO 63110-1093, USA.
Wu DY; Department of Neuroscience, Washington University School of Medicine, St Louis, MO 63110-1093, USA.
Clemens AW; Department of Neuroscience, Washington University School of Medicine, St Louis, MO 63110-1093, USA.
Nettles SA; Department of Neuroscience, Washington University School of Medicine, St Louis, MO 63110-1093, USA.
Li A; Department of Neuroscience, Washington University School of Medicine, St Louis, MO 63110-1093, USA.
Gabel HW; Department of Neuroscience, Washington University School of Medicine, St Louis, MO 63110-1093, USA. Electronic address: gabelh@wustl.edu.

Mol Cell ; 83(9): 1412-1428.e7, 2023 05 04.

Article en En | MEDLINE | ID: mdl-37098340

Asunto(s)

Metilación de ADN; Histonas; Animales; Ratones; Histonas/genética; Histonas/metabolismo; Lisina/metabolismo; N-Metiltransferasa de Histona-Lisina/genética; N-Metiltransferasa de Histona-Lisina/metabolismo; Neuronas/metabolismo

Palabras clave

DNA methylation; DNMT3A; NSD1; Sotos syndrome; genome topology; histone methylation; neurodevelopmental disease; non-CG methylation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Histonas / Metilación de ADN Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Cell Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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