Your browser doesn't support javascript.
loading
Tramadol May Increase Risk of Hip Fracture in Older Adults with Post-Traumatic Osteoarthritis.
Wu, Ting-Yu; Wu, Wen-Tien; Lee, Ru-Ping; Chen, Ing-Ho; Yu, Tzai-Chiu; Wang, Jen-Hung; Yeh, Kuang-Ting.
Afiliación
  • Wu TY; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.
  • Wu WT; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.
  • Lee RP; School of Medicine, Tzu Chi University, Hualien 970374, Taiwan.
  • Chen IH; Institute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan.
  • Yu TC; Institute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan.
  • Wang JH; Department of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.
  • Yeh KT; School of Medicine, Tzu Chi University, Hualien 970374, Taiwan.
J Pers Med ; 13(4)2023 Mar 26.
Article en En | MEDLINE | ID: mdl-37108965
Tramadol, an analgesic widely used for arthritic pain, is known to have adverse effects. This study investigated the association between the long-term use of tramadol for pain control and subsequent hip fractures in patients aged 60 years or older with posttraumatic osteoarthritis. This population-based retrospective cohort study included patients with posttraumatic osteoarthritis who received tramadol for pain control for more than 90 days within a 1-year period. A control cohort was enrolled using propensity score matching. The primary outcome was a new diagnosis of hip fracture requiring surgery. In total, 3093 patients were classified into each cohort. Tramadol use was identified as a risk factor for hip fracture (adjusted hazard ratio (aHR): 1.41; 95% confidence interval (CI): 1.09-1.82; p = 0.008), especially among patients aged 60-70 years (aHR: 2.11; 95% CI: 1.29-3.47; p = 0.003) and among male patients (aHR: 1.83; 95% CI: 1.24-2.70; p = 0.002). This is the first cohort study focusing on the association between long-term tramadol use and hip fracture among older adults with posttraumatic osteoarthritis. Tramadol, as a long-term pain control analgesic for older adults with posttraumatic osteoarthritis, may increase the risk of hip fracture, especially among male patients and those aged 60-70 years.
Palabras clave

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Pers Med Año: 2023 Tipo del documento: Article País de afiliación: Taiwán

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Pers Med Año: 2023 Tipo del documento: Article País de afiliación: Taiwán