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Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions.
Nag, Arundhati; Mafi, Amirhossein; Das, Samir; Yu, Mary Beth; Alvarez-Villalonga, Belen; Kim, Soo-Kyung; Su, Yapeng; Goddard, William A; Heath, James R.
Afiliación
  • Nag A; California Institute of Technology, Pasadena, CA, USA.
  • Mafi A; Clark University, Worcester, MA, USA.
  • Das S; Materials and Process Simulation Center (139-74), California Institute of Technology, Pasadena, CA, USA.
  • Yu MB; California Institute of Technology, Pasadena, CA, USA.
  • Alvarez-Villalonga B; Clark University, Worcester, MA, USA.
  • Kim SK; California Institute of Technology, Pasadena, CA, USA.
  • Su Y; California Institute of Technology, Pasadena, CA, USA.
  • Goddard WA; Materials and Process Simulation Center (139-74), California Institute of Technology, Pasadena, CA, USA.
  • Heath JR; California Institute of Technology, Pasadena, CA, USA.
Commun Chem ; 6(1): 95, 2023 May 18.
Article en En | MEDLINE | ID: mdl-37202473
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Commun Chem Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Commun Chem Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos