Added Value of Internal Fragments for Top-Down Mass Spectrometry of Intact Monoclonal Antibodies and Antibody-Drug Conjugates.

Wei, Benqian; Lantz, Carter; Liu, Weijing; Viner, Rosa; Ogorzalek Loo, Rachel R; Campuzano, Iain D G; Loo, Joseph A

Wei, Benqian; Lantz, Carter; Liu, Weijing; Viner, Rosa; Ogorzalek Loo, Rachel R; Campuzano, Iain D G; Loo, Joseph A.

Afiliación

Wei B; Department of Chemistry and Biochemistry, University of CaliforniaâLos Angeles, Los Angeles, California 90095, United States.
Lantz C; Department of Chemistry and Biochemistry, University of CaliforniaâLos Angeles, Los Angeles, California 90095, United States.
Liu W; Thermo Fisher Scientific, San Jose, California 95134, United States.
Viner R; Thermo Fisher Scientific, San Jose, California 95134, United States.
Ogorzalek Loo RR; Department of Chemistry and Biochemistry, University of CaliforniaâLos Angeles, Los Angeles, California 90095, United States.
Campuzano IDG; UCLA-DOE Institute, University of CaliforniaâLos Angeles, Los Angeles, California 90095, United States.
Loo JA; Molecular Biology Institute, University of CaliforniaâLos Angeles, Los Angeles, California 90095, United States.

Anal Chem ; 95(24): 9347-9356, 2023 06 20.

Article en En | MEDLINE | ID: mdl-37278738

Asunto(s)

Espectrometría de Masas; Anticuerpos Monoclonales/química; Humanos; Glicosilación; Espectrometría de Masas/métodos; Disulfuros/química; Lisina/química

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Espectrometría de Masas Límite: Humans Idioma: En Revista: Anal Chem Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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