Meta-analysis of single-cell and single-nucleus transcriptomics reveals kidney cell type consensus signatures.
Sci Data
; 10(1): 361, 2023 06 06.
Article
en En
| MEDLINE
| ID: mdl-37280226
ABSTRACT
While the amount of studies involving single-cell or single-nucleus RNA-sequencing technologies grows exponentially within the biomedical research area, the kidney field requires reference transcriptomic signatures to allocate each cluster its matching cell type. The present meta-analysis of 39 previously published datasets, from 7 independent studies, involving healthy human adult kidney samples, offers a set of 24 distinct consensus kidney cell type signatures. The use of these signatures may help to assure the reliability of cell type identification in future studies involving single-cell and single-nucleus transcriptomics while improving the reproducibility in cell type allocation.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Transcriptoma
/
Riñón
Tipo de estudio:
Prognostic_studies
/
Systematic_reviews
Límite:
Adult
/
Humans
Idioma:
En
Revista:
Sci Data
Año:
2023
Tipo del documento:
Article
País de afiliación:
Francia