1-Methylnicotinamide (1-MNA) inhibits the activation of the NLRP3 inflammasome in human macrophages.

Sidor, Karolina; Jeznach, Aldona; Hoser, Grazyna; Skirecki, Tomasz

Sidor, Karolina; Jeznach, Aldona; Hoser, Grazyna; Skirecki, Tomasz.

Afiliación

Sidor K; Department of Translational Immunology and Experimental Intensive Care, Centre of Postgraduate Medical Education, Warsaw, Poland.
Jeznach A; Department of Translational Immunology and Experimental Intensive Care, Centre of Postgraduate Medical Education, Warsaw, Poland.
Hoser G; Department of Translational Immunology and Experimental Intensive Care, Centre of Postgraduate Medical Education, Warsaw, Poland.
Skirecki T; Department of Translational Immunology and Experimental Intensive Care, Centre of Postgraduate Medical Education, Warsaw, Poland. Electronic address: tskirecki@cmkp.edu.pl.

Int Immunopharmacol ; 121: 110445, 2023 Aug.

Article en En | MEDLINE | ID: mdl-37290319

Asunto(s)

Inflamasomas; Proteína con Dominio Pirina 3 de la Familia NLR; Humanos; Inflamasomas/metabolismo; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Peróxido de Hidrógeno/metabolismo; Macrófagos/metabolismo; Niacinamida; Interleucina-1beta/metabolismo; Caspasa 1/metabolismo

Palabras clave

Inflammasome; Inflammation; Innate immunity; Pattern-recognition receptors; Reactive oxygen species

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR Límite: Humans Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Polonia

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