[Prostate cancer in older men : Special features of the diagnostics and treatment]. / Prostatakarzinom beim älteren Mann : Besonderheiten der Diagnostik und Therapie.
Z Gerontol Geriatr
; 56(4): 324-334, 2023 Jul.
Article
en De
| MEDLINE
| ID: mdl-37306771
ABSTRACT
Prostate cancer is the most frequent cancer in men. For localized prostate cancer, surgery and radiotherapy are the standard treatment, with active surveillance also used in low-risk cases. For advanced/metastatic disease, androgen deprivation treatment is carried out. Further options include inhibitors of the androgen receptor axis and taxane-based chemotherapy. The avoidance of side effects should be considered, e.g., by dose adjustment. New options include poly(ADP-ribose) polymerase (PARP) inhibitors, and radioligand treatment. The existing guidelines only provide a few treatment recommendations for older patients; however, the treatment of older patients should primarily consider not only chronological age but also the patient's psychological and physical condition and preferences. In this context, the geriatric assessment represents an important instrument for determining the treatment strategy.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias de la Próstata
Tipo de estudio:
Diagnostic_studies
/
Guideline
Límite:
Aged
/
Humans
/
Male
Idioma:
De
Revista:
Z Gerontol Geriatr
Asunto de la revista:
GERIATRIA
Año:
2023
Tipo del documento:
Article