Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress.

Endesh, Naima; Chuntharpursat-Bon, Eulashini; Revill, Charlotte; Yuldasheva, Nadira Y; Futers, T Simon; Parsonage, Gregory; Humphreys, Neil; Adamson, Antony; Morley, Lara C; Cubbon, Richard M; Prasad, K Raj; Foster, Richard; Lichtenstein, Laeticia; Beech, David J

Endesh, Naima; Chuntharpursat-Bon, Eulashini; Revill, Charlotte; Yuldasheva, Nadira Y; Futers, T Simon; Parsonage, Gregory; Humphreys, Neil; Adamson, Antony; Morley, Lara C; Cubbon, Richard M; Prasad, K Raj; Foster, Richard; Lichtenstein, Laeticia; Beech, David J.

Afiliación

Endesh N; School of Medicine, University of Leeds, Leeds, UK.
Chuntharpursat-Bon E; School of Medicine, University of Leeds, Leeds, UK.
Revill C; School of Chemistry, University of Leeds, Leeds, UK.
Yuldasheva NY; School of Medicine, University of Leeds, Leeds, UK.
Futers TS; School of Medicine, University of Leeds, Leeds, UK.
Parsonage G; School of Medicine, University of Leeds, Leeds, UK.
Humphreys N; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Adamson A; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Morley LC; School of Medicine, University of Leeds, Leeds, UK.
Cubbon RM; School of Medicine, University of Leeds, Leeds, UK.
Prasad KR; Department of Hepatobiliary and Transplant Surgery, St James's University Hospital, Leeds, UK.
Foster R; School of Chemistry, University of Leeds, Leeds, UK.
Lichtenstein L; School of Medicine, University of Leeds, Leeds, UK.
Beech DJ; School of Medicine, University of Leeds, Leeds, UK.

Liver Int ; 43(9): 2026-2038, 2023 09.

Article en En | MEDLINE | ID: mdl-37349903

Asunto(s)

Canales Iónicos; Óxido Nítrico; Vena Porta; Canales Catiónicos TRPV; Animales; Masculino; Ratones; Endotelio/metabolismo; Óxido Nítrico Sintasa/metabolismo; Presión Osmótica; Canales Catiónicos TRPV/genética; Canales Catiónicos TRPV/metabolismo; Vasodilatación; Canales Iónicos/genética; Canales Iónicos/metabolismo

Palabras clave

PIEZO channel; arachidonic acid metabolism; calcium signalling; calcium-permeable channel; endothelial nitric oxide synthase; endothelium; hepatobiliary system; liver; mechanical force; nitric oxide; non-selective cation channel; osmolality; portal vein; transient receptor potential vanilloid 4 (TRPV4) channel; vascular relaxation; vasculature contraction; vein

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Vena Porta / Canales Catiónicos TRPV / Canales Iónicos / Óxido Nítrico Límite: Animals Idioma: En Revista: Liver Int Asunto de la revista: GASTROENTEROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido

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