Hippocampal delivery of neurotrophic factor-&#945;1/carboxypeptidase E gene prevents neurodegeneration, amyloidosis, memory loss in Alzheimer's Disease male mice.

Xiao, Lan; Yang, Xuyu; Sharma, Vinay Kumar; Abebe, Daniel; Loh, Y Peng

Hippocampal delivery of neurotrophic factor-α1/carboxypeptidase E gene prevents neurodegeneration, amyloidosis, memory loss in Alzheimer's Disease male mice.

Xiao, Lan; Yang, Xuyu; Sharma, Vinay Kumar; Abebe, Daniel; Loh, Y Peng.

Afiliación

Xiao L; Section on Cellular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md, 20892, USA.
Yang X; Section on Cellular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md, 20892, USA.
Sharma VK; Section on Cellular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md, 20892, USA.
Abebe D; Section on Cellular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md, 20892, USA.
Loh YP; Section on Cellular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md, 20892, USA. lohp@mail.nih.gov.

Mol Psychiatry ; 28(8): 3332-3342, 2023 Aug.

Article en En | MEDLINE | ID: mdl-37369719

Asunto(s)

Enfermedad de Alzheimer; Amiloidosis; Enfermedades Neurodegenerativas; Ratones; Masculino; Animales; Enfermedad de Alzheimer/metabolismo; Carboxipeptidasa H/genética; Carboxipeptidasa H/metabolismo; Enfermedades Neurodegenerativas/metabolismo; Péptidos beta-Amiloides/metabolismo; Hipocampo/metabolismo; Trastornos de la Memoria/genética; Trastornos de la Memoria/prevención & control; Trastornos de la Memoria/metabolismo; Precursor de Proteína beta-Amiloide/genética; Precursor de Proteína beta-Amiloide/metabolismo; Factores de Crecimiento Nervioso/metabolismo; Amiloidosis/genética; Amiloidosis/metabolismo; Amnesia/metabolismo; Ratones Transgénicos; Modelos Animales de Enfermedad; Proteínas tau/genética; Proteínas tau/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedades Neurodegenerativas / Enfermedad de Alzheimer / Amiloidosis Límite: Animals Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google