Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes.

Hartung, Ingo V; Rudolph, Joachim; Mader, Mary M; Mulder, Monique P C; Workman, Paul

Hartung, Ingo V; Rudolph, Joachim; Mader, Mary M; Mulder, Monique P C; Workman, Paul.

Afiliación

Hartung IV; Medicinal Chemistry, Global Research & Development, Merck Healthcare KGaA, 64293 Darmstadt, Germany.
Rudolph J; Discovery Chemistry, Genentech, South San Francisco, California 94080, United States.
Mader MM; Molecular Innovation, Indiana Biosciences Research Institute, Indianapolis, Indiana 64202, United States.
Mulder MPC; Department of Cell and Chemical Biology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Workman P; Centre for Cancer Drug Discovery, The Institute of Cancer Research, London, Sutton SM2 5NG, United Kingdom.

J Med Chem ; 66(14): 9297-9312, 2023 07 27.

Article en En | MEDLINE | ID: mdl-37403870

Asunto(s)

Ubiquitina-Proteína Ligasas; Proteolisis

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ubiquitina-Proteína Ligasas Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Alemania

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