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PD-L1 dimerisation induced by biphenyl derivatives mediates anti-breast cancer activity via the non-immune PD-L1-AKT-mTOR/Bcl2 pathway.
Zhang, Hua; Zhou, Shi-Jia; Shen, Chen-Feng; Zhou, Yong-Nan; Wu, Cai-Yun; Zhu, Meng-Yu; Yu, Qi-Meng; Awadasseid, Annoor; Wu, Yan-Ling; Zhang, Wen.
Afiliación
  • Zhang H; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
  • Zhou SJ; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou, China.
  • Shen CF; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
  • Zhou YN; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou, China.
  • Wu CY; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
  • Zhu MY; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou, China.
  • Yu QM; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
  • Awadasseid A; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou, China.
  • Wu YL; Lab of Chemical Biology and Molecular Drug Design, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, China.
  • Zhang W; Institute of Drug Development & Chemical Biology, Zhejiang University of Technology, Hangzhou, China.
J Enzyme Inhib Med Chem ; 38(1): 2230388, 2023 Dec.
Article en En | MEDLINE | ID: mdl-37439326
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Compuestos de Bifenilo / Neoplasias de la Mama / Proteínas Proto-Oncogénicas c-akt Límite: Animals Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Compuestos de Bifenilo / Neoplasias de la Mama / Proteínas Proto-Oncogénicas c-akt Límite: Animals Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China