The Relationship between the MAGGIC Score and Cardiorenal Syndrome in Patients with Acute Decompensated Heart Failure with Reduced Ejection Fraction.
Acta Cardiol Sin
; 39(4): 610-618, 2023 Jul.
Article
en En
| MEDLINE
| ID: mdl-37456933
ABSTRACT
Background:
The Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC) is a scoring system that is easy to use in outpatient clinics or at the bedside, and was developed to predict the survival of heart failure patients after hospitalization.Objectives:
This study aims to evaluate the relationship between the MAGGIC score and cardiorenal syndrome (CRS) in patients with acute decompensated heart failure with reduced ejection fraction (HFrEF).Methods:
This retrospective, single-center study, included 706 patients with New York Heart Association II-IV who were hospitalized and discharged for acute decompensated heart failure between 2016 and 2021. CRS type 1 was defined as acute worsening of cardiac function leading to renal dysfunction. Patients were divided into two groups those with CRS and those without. The MAGGIC score of all patients was determined. The primary outcome was the occurrence of CRS.Results:
CRS developed in 132 patients. The MAGGIC score was higher in CRS (+) patients compared to CRS (-) patients (30.70 ± 8.09 vs. 23.96 ± 5.59, p < 0.001). After a multivariable analysis, MAGGIC score [odds ratio (OR) 3.92, p < 0.001], sodium (OR 0.92, p = 0.003), N terminal pro B type natriuretic peptide (OR 1.78, p = 0.009), hs troponin (OR 1.28, p = 0.044), MRA (OR 0.61, p = 0.019) and furosemide dose (OR 1.03, p = 0.001) were found to be independent predictors of CRS development. The MAGGIC score was associated with CRS development (area under curve = 0.778).Conclusions:
The MAGGIC score may be associated with CRS in HFrEF patients.
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Bases de datos:
MEDLINE
Tipo de estudio:
Prognostic_studies
Idioma:
En
Revista:
Acta Cardiol Sin
Año:
2023
Tipo del documento:
Article