Integrated analysis of FKBP1A/SLC3A2 axis in everolimus inducing ferroptosis of breast cancer and anti-proliferation of T lymphocyte.

Chen, Zihan; Li, Rongxue; Fang, Min; Wang, Ying; Bi, Aihong; Yang, Lixian; Song, Tao; Li, Yucheng; Li, Qiang; Lin, Baihua; Jia, Yongshi; Fu, Shi; Fu, Shuiqiao; Xiong, Hanchu

Chen, Zihan; Li, Rongxue; Fang, Min; Wang, Ying; Bi, Aihong; Yang, Lixian; Song, Tao; Li, Yucheng; Li, Qiang; Lin, Baihua; Jia, Yongshi; Fu, Shi; Fu, Shuiqiao; Xiong, Hanchu.

Afiliación

Chen Z; Surgical Intensive Care Unit, First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, 310016, China.
Li R; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Fang M; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Wang Y; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Bi A; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Yang L; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Song T; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Li Y; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Li Q; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Lin B; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Jia Y; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.
Fu S; Surgical Intensive Care Unit, First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, 310016, China.
Fu S; Surgical Intensive Care Unit, First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, 310016, China.
Xiong H; Cancer Center, Department of Radiation Oncology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.

Int J Med Sci ; 20(8): 1060-1078, 2023.

Article en En | MEDLINE | ID: mdl-37484811

Asunto(s)

Neoplasias de la Mama; Ferroptosis; Humanos; Femenino; Everolimus/farmacología; Everolimus/uso terapéutico; Proteína 1A de Unión a Tacrolimus/metabolismo; Ferroptosis/genética; Recurrencia Local de Neoplasia; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/genética; Neoplasias de la Mama/metabolismo; Microambiente Tumoral/genética; Cadena Pesada de la Proteína-1 Reguladora de Fusión/genética; Cadena Pesada de la Proteína-1 Reguladora de Fusión/metabolismo; Proteínas de Unión a Tacrolimus/genética; Proteínas de Unión a Tacrolimus/metabolismo

Palabras clave

Breast cancer; Everolimus; FKBP1A; Ferroptosis; SLC3A2; Th9.

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Ferroptosis Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Int J Med Sci Asunto de la revista: MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: China

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