[Risk and Mortality Factors for Pleural Effusions Requiring Diagnostic Thoracentesis]. / Factores de riesgo y mortalidad de los derrames pleurales que precisan de una toracocentesis diagnóstica.
Open Respir Arch
; 4(4): 100201, 2022.
Article
en Es
| MEDLINE
| ID: mdl-37496966
ABSTRACT
Introduction:
Occurrence of malignant pleural effusion (PE) is known to be associated with a poor prognosis, but the mortality of patients with non-malignant effusions has not been sufficiently studied. Our objective was to describe the clinical course and explore risk factors associated with all-cause mortality at 1, 5 and 10 years in patients who develop a PE.Methods:
Retrospective observational study of patients undergoing diagnostic thoracentesis during the decade 2008-2017 in a pulmonology service. Demographic, biochemical, pathological and evolutionary variables were evaluated. The etiology of the effusions was determined using standardized criteria.Results:
Pleural fluid samples from 358 patients with a mean age of 68.9 years (SD 15.1 years), 69.2% males, were analyzed. Malignant (29.4%), parapneumonic (19.8%) and secondary to heart failure (18.9%) effusions predominated. Patients with malignant and heart failure related PE had 1-year mortality rates of 60.0% and 30.8%, respectively, and 85% and 64.7% at 5 years. Male gender (hazard ratio [HR] 1.46; 95% CI 1.03-2.07), positive cytology for malignancy (HR 1.66; 95% CI 1.03-2.68) and effusion recurrence (HR 1.61; 95% CI 1.17-2.21) were associated with a worse prognosis and 5-year mortality.Conclusions:
Patients undergoing thoracentesis for effusion have a high short and long-term mortality. In our series of hospitalized patients with PE, the factors associated with higher mortality at 1 and 5 years were age, male sex, recurrence of PE, and coexistence of malignancy.
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Bases de datos:
MEDLINE
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
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Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Idioma:
Es
Revista:
Open Respir Arch
Año:
2022
Tipo del documento:
Article