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PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models.
Wong, Chun Wai; Evangelou, Christos; Sefton, Kieran N; Leshem, Rotem; Zhang, Wei; Gopalan, Vishaka; Chattrakarn, Sorayut; Fernandez Carro, Macarena Lucia; Uzuner, Erez; Mole, Holly; Wilcock, Daniel J; Smith, Michael P; Sergiou, Kleita; Telfer, Brian A; Isaac, Dervla T; Liu, Chang; Perl, Nicholas R; Marie, Kerrie; Lorigan, Paul; Williams, Kaye J; Rao, Patricia E; Nagaraju, Raghavendar T; Niepel, Mario; Hurlstone, Adam F L.
Afiliación
  • Wong CW; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Evangelou C; Lydia Becker Institute of Immunology, The University of Manchester, Manchester, M13 9PT, UK.
  • Sefton KN; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Leshem R; Lydia Becker Institute of Immunology, The University of Manchester, Manchester, M13 9PT, UK.
  • Zhang W; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Gopalan V; Lydia Becker Institute of Immunology, The University of Manchester, Manchester, M13 9PT, UK.
  • Chattrakarn S; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Fernandez Carro ML; Lydia Becker Institute of Immunology, The University of Manchester, Manchester, M13 9PT, UK.
  • Uzuner E; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Mole H; Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD, 20814, USA.
  • Wilcock DJ; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Smith MP; Lydia Becker Institute of Immunology, The University of Manchester, Manchester, M13 9PT, UK.
  • Sergiou K; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Telfer BA; Lydia Becker Institute of Immunology, The University of Manchester, Manchester, M13 9PT, UK.
  • Isaac DT; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Liu C; Lydia Becker Institute of Immunology, The University of Manchester, Manchester, M13 9PT, UK.
  • Perl NR; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Marie K; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Lorigan P; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Williams KJ; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Rao PE; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK.
  • Nagaraju RT; Ribon Therapeutics Inc., 35 Cambridge Park Drive, Suite 300, Cambridge, MA, 02140, USA.
  • Niepel M; Ribon Therapeutics Inc., 35 Cambridge Park Drive, Suite 300, Cambridge, MA, 02140, USA.
  • Hurlstone AFL; Ribon Therapeutics Inc., 35 Cambridge Park Drive, Suite 300, Cambridge, MA, 02140, USA.
Nat Commun ; 14(1): 5983, 2023 09 26.
Article en En | MEDLINE | ID: mdl-37752135
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inhibidores de Puntos de Control Inmunológico / Melanoma Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inhibidores de Puntos de Control Inmunológico / Melanoma Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido