A Case of Immune Thrombocytopenia Occurring after Radiotherapy plus Atezolizumab Treatment for Bladder Cancer.
Gan To Kagaku Ryoho
; 50(9): 985-992, 2023 Sep.
Article
en En
| MEDLINE
| ID: mdl-37800294
ABSTRACT
An 84-year-old female developed gross hematuria. She was diagnosed as urinary bladder carcinoma. She was initiated on concurrent atezolizumab plus radiation(a phase â
¡ clinical trial)(jRCT2031180060). After 8 cycles of atezolizumab, complete response was confirmed. Maintenance atezolizumab treatment was started. Platelet(Plt)count decreased, there was no rechallenge with atezolizumab. Bone marrow examination revealed normal. Plt count recovered. Plt count decreased again. The serum levels of interleukin-6(IL-6)were elevated. She was diagnosed as having immune thrombocytopenia. She was started on treatment with prednisolone(PSL)at dose of 20 mg/day. Plt count was increased.
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Bases de datos:
MEDLINE
Asunto principal:
Trombocitopenia
/
Neoplasias de la Vejiga Urinaria
/
Púrpura Trombocitopénica Idiopática
Límite:
Aged80
/
Female
/
Humans
Idioma:
En
Revista:
Gan To Kagaku Ryoho
Año:
2023
Tipo del documento:
Article