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The Orphan Drug for Acanthamoeba Keratitis (ODAK) Trial: PHMB 0.08% (Polihexanide) and Placebo versus PHMB 0.02% and Propamidine 0.1.
Dart, John K G; Papa, Vincenzo; Rama, Paolo; Knutsson, Karl Anders; Ahmad, Saj; Hau, Scott; Sanchez, Sara; Franch, Antonella; Birattari, Federica; Leon, Pia; Fasolo, Adriano; Kominek, Ewa Mrukwa; Jadczyk-Sorek, Katarzyna; Carley, Fiona; Hossain, Parwez; Minassian, Darwin C.
Afiliación
  • Dart JKG; Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom; National Institute of Health Research, Moorfields Biomedical Research Centre, London, United Kingdom.
  • Papa V; Medical Affairs, SiFi SpA, Catania, Italy.
  • Rama P; Cornea and Ocular Surface Unit, San Raffaele Scientific Institute, Milan, Italy.
  • Knutsson KA; Cornea and Ocular Surface Unit, San Raffaele Scientific Institute, Milan, Italy.
  • Ahmad S; Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom; National Institute of Health Research, Moorfields Biomedical Research Centre, London, United Kingdom.
  • Hau S; Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom; National Institute of Health Research, Moorfields Biomedical Research Centre, London, United Kingdom.
  • Sanchez S; Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom.
  • Franch A; Ophthalmic Unit, Ospedale SS Giovanni e Paolo, Venice, Italy.
  • Birattari F; Ophthalmic Unit, Ospedale SS Giovanni e Paolo, Venice, Italy.
  • Leon P; Ophthalmic Unit, Ospedale SS Giovanni e Paolo, Venice, Italy.
  • Fasolo A; Research Unit, The Veneto Eye Bank Foundation, Venice, Italy.
  • Kominek EM; Professor K. Gibinski University Clinical Center of Medical University of Silesia in Katowice, Katowice, Poland; Department of Ophthalmology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Katowice, Poland.
  • Jadczyk-Sorek K; Professor K. Gibinski University Clinical Center of Medical University of Silesia in Katowice, Katowice, Poland; Department of Ophthalmology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Katowice, Poland.
  • Carley F; Manchester Royal Eye Hospital, Manchester, United Kingdom.
  • Hossain P; Clinical Experimental Sciences, Faculty of Medicine, University of Southampton & University Hospitals Southampton NHS Trust, Southampton, United Kingdom; National Institute of Health Research (NIHR), Southampton Clinical Research Facility, Southampton, United Kingdom.
  • Minassian DC; EpiVision Ophthalmic Epidemiology Consultants, Penn, United Kingdom.
Ophthalmology ; 131(3): 277-287, 2024 Mar.
Article en En | MEDLINE | ID: mdl-37802392

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Benzamidinas / Biguanidas / Queratitis por Acanthamoeba Tipo de estudio: Clinical_trials / Guideline / Risk_factors_studies Límite: Humans Idioma: En Revista: Ophthalmology Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Benzamidinas / Biguanidas / Queratitis por Acanthamoeba Tipo de estudio: Clinical_trials / Guideline / Risk_factors_studies Límite: Humans Idioma: En Revista: Ophthalmology Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido