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Complex haploinsufficiency in pluripotent cells yields somatic cells with DNA methylation abnormalities and pluripotency induction defects.
Lasry, Rachel; Maoz, Noam; Cheng, Albert W; Yom Tov, Nataly; Kulenkampff, Elisabeth; Azagury, Meir; Yang, Hui; Ople, Cora; Markoulaki, Styliani; Faddah, Dina A; Makedonski, Kirill; Orzech, Dana; Sabag, Ofra; Jaenisch, Rudolf; Buganim, Yosef.
Afiliación
  • Lasry R; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
  • Maoz N; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
  • Cheng AW; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Yom Tov N; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
  • Kulenkampff E; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Azagury M; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
  • Yang H; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Ople C; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Markoulaki S; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Faddah DA; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Makedonski K; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
  • Orzech D; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
  • Sabag O; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
  • Jaenisch R; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Buganim Y; Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel. Electronic address: yossib@ekmd.huji.ac.il.
Stem Cell Reports ; 18(11): 2174-2189, 2023 11 14.
Article en En | MEDLINE | ID: mdl-37832543
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Metilación de ADN / Células Madre Pluripotentes Inducidas Idioma: En Revista: Stem Cell Reports Año: 2023 Tipo del documento: Article País de afiliación: Israel
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Metilación de ADN / Células Madre Pluripotentes Inducidas Idioma: En Revista: Stem Cell Reports Año: 2023 Tipo del documento: Article País de afiliación: Israel