Efficacy, Safety, and Tolerability of Inclisiran in Patients With Homozygous Familial Hypercholesterolemia: Results From the ORION-5 Randomized Clinical Trial.

Raal, Frederick; Durst, Ronen; Bi, Ran; Talloczy, Zsolt; Maheux, Pierre; Lesogor, Anastasia; Kastelein, John J P

Raal, Frederick; Durst, Ronen; Bi, Ran; Talloczy, Zsolt; Maheux, Pierre; Lesogor, Anastasia; Kastelein, John J P.

Afiliación

Raal F; Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (F.R.).
Durst R; Cardiology Department, Hadassah-Hebrew University Medical Centre, Jerusalem, Israel (R.D.).
Bi R; Novartis Pharmaceuticals Corporation, East Hannover, NJ (R.B., Z.T.).
Talloczy Z; Novartis Pharmaceuticals Corporation, East Hannover, NJ (R.B., Z.T.).
Maheux P; Novartis Pharmaceuticals Corporation, Basel, Switzerland (P.M., A.L.).
Lesogor A; Novartis Pharmaceuticals Corporation, Basel, Switzerland (P.M., A.L.).
Kastelein JJP; Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Netherlands (J.J.P.K.).

Circulation ; 149(5): 354-362, 2024 01 30.

Article en En | MEDLINE | ID: mdl-37850379

Asunto(s)

Anticolesterolemiantes; Hipercolesterolemia Familiar Homocigótica; Inhibidores de Hidroximetilglutaril-CoA Reductasas; Humanos; Femenino; Adulto; Masculino; Proproteína Convertasa 9/metabolismo; LDL-Colesterol; Inhibidores de Hidroximetilglutaril-CoA Reductasas/efectos adversos; ARN Interferente Pequeño/efectos adversos; Colesterol; Anticolesterolemiantes/efectos adversos

Palabras clave

cholesterol; homozygous familial hypercholesterolemia; lipoproteins, LDL; therapeutics

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inhibidores de Hidroximetilglutaril-CoA Reductasas / Hipercolesterolemia Familiar Homocigótica / Anticolesterolemiantes Límite: Adult / Female / Humans / Male Idioma: En Revista: Circulation Año: 2024 Tipo del documento: Article

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