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Identification of Novel and Early Biomarkers for Cisplatin-induced Nephrotoxicity and the Nephroprotective Role of Cimetidine using a Pharmacometabolomic-based Approach Coupled with In Vitro Toxicodynamic Modeling and Simulation.
Mody, Hardik; Nair, Sreenath; Rump, Adrian; Vaidya, Tanaya R; Garrett, Timothy J; Lesko, Lawrence; Ait-Oudhia, Sihem.
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  • Mody H; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, FL, USA.
  • Nair S; Pharmaceutical Sciences Department, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Rump A; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, FL, USA.
  • Vaidya TR; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, FL, USA.
  • Garrett TJ; Southeast Center for Integrated Metabolomics, University of Florida, Gainesville, FL, USA.
  • Lesko L; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, FL, USA.
  • Ait-Oudhia S; Quantitative Pharmacology and Pharmacometrics (QP2), Merck & Co., Inc, Rahway, NJ, USA. Electronic address: sb.manuscript.submission@gmail.com.
J Pharm Sci ; 113(1): 268-277, 2024 01.
Article en En | MEDLINE | ID: mdl-37992870
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cisplatino / Antineoplásicos Límite: Humans Idioma: En Revista: J Pharm Sci Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cisplatino / Antineoplásicos Límite: Humans Idioma: En Revista: J Pharm Sci Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos