Association of isolated bovine kidney cortex peroxisomes with endoplasmic reticulum.
Biochim Biophys Acta
; 897(1): 135-42, 1987 Feb 12.
Article
en En
| MEDLINE
| ID: mdl-3801475
ABSTRACT
Close lateral membrane associations of peroxisomes with endoplasmic reticulum are a common feature in bovine kidney cortex epithelial cells. Isolated highly purified peroxisome preparations from this tissue showed a remarkable and persistent copurification of peroxisomal marker enzymes with small amounts (5%) of the microsomal reference enzymes esterase and glucose-6-phosphatase. Contamination with mitochondrial and lysosomal markers was negligible. Ultrastructural examination of such preparations revealed a peculiar association of vesicles or short tubular segments with the peroxisomal membrane. Short electron dense crossbridges seemed to maintain their structural association. The cytochemical localization of glucose-6-phosphatase in peroxisome-associated membrane structures confirmed their derivation from endoplasmic reticulum. The metabolic significance of such structural peroxisome-endoplasmic reticulum associations is discussed.
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Bases de datos:
MEDLINE
Asunto principal:
Retículo Endoplásmico
/
Corteza Renal
/
Microcuerpos
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
Idioma:
En
Revista:
Biochim Biophys Acta
Año:
1987
Tipo del documento:
Article