Role of immunometabolism during congenital cytomegalovirus infection.
Immunometabolism (Cobham)
; 5(4): e00034, 2023 Oct.
Article
en En
| MEDLINE
| ID: mdl-38037590
ABSTRACT
Cytomegalovirus (CMV) is a master manipulator of host metabolic pathways. The impact of CMV metabolic rewiring during congenital CMV on immune function is unknown. CMV infection can directly alter glycolytic and oxidative phosphorylation pathways in infected cells. Recent data suggests CMV may alter metabolism in uninfected neighboring cells. In this mini review, we discuss how CMV infection may impact immune function through metabolic pathways. We discuss how immune cells differ between maternal and decidual compartments and how altered immunometabolism may contribute to congenital infections.
Texto completo:
1
Bases de datos:
MEDLINE
Idioma:
En
Revista:
Immunometabolism (Cobham)
Año:
2023
Tipo del documento:
Article
País de afiliación:
Estados Unidos