Research progress on chemical modifications of tyrosine residues in peptides and proteins.
Biotechnol Bioeng
; 121(3): 799-822, 2024 Mar.
Article
en En
| MEDLINE
| ID: mdl-38079153
ABSTRACT
The chemical modifications (CMs) of protein is an important technique in chemical biology, protein-based therapy, and material science. In recent years, there has been rapid advances in the development of CMs of peptides and proteins, providing new approaches for peptide and protein functionalization, as well as drug discovery. In this review, we highlight the methods for chemically modifying tyrosine (Tyr) residues in different regions, offering a comprehensive exposition of the research content related to Tyr modification. This review summarizes and provides an outlook on Tyr residue modification, aiming to offer readers assistance in the site-selective modification of macromolecules and to facilitate application research in this field.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Péptidos
/
Tirosina
Idioma:
En
Revista:
Biotechnol Bioeng
Año:
2024
Tipo del documento:
Article
País de afiliación:
China