Cytotoxic Th1 cells mushroom after fungal exposures in Crohn's disease.

Strazar, Martin; Xavier, Ramnik J

Strazar, Martin; Xavier, Ramnik J.

Afiliación

Strazar M; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address: mstrazar@broadinstitute.org.
Xavier RJ; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Computational and Integrative Biology and Department of Molecular Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: xavier@molbio.mgh.harvard.edu.

Immunity ; 56(12): 2679-2681, 2023 Dec 12.

Article en En | MEDLINE | ID: mdl-38091949

ABSTRACT

ABSTRACT

Fungi are consistently enriched in inflamed intestines, with elusive effects on host immunity. In a recent issue of Nature Medicine, Martini et al. identify a subset of Th1 cells able to lyse the epithelium, enriched in Crohn's disease patient samples after fungal exposure.

Asunto(s)

Agaricales; Enfermedad de Crohn; Humanos; Células TH1; Intestinos/microbiología

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Crohn / Agaricales Límite: Humans Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2023 Tipo del documento: Article

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