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Gastrointestinal fate of blueberry anthocyanins in ferritin-based nanocarriers.
Herrera-Balandrano, Daniela D; Chai, Zhi; Cui, Li; Zhao, Xingyu; Zhao, Xuan; Li, Bin; Yang, Yiyun; Huang, Wuyang.
Afiliación
  • Herrera-Balandrano DD; School of Life Sciences, Nantong University, Nantong 226019, China; Institute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China. Electronic address: daniela.herrera@ntu.edu.cn.
  • Chai Z; Institute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China. Electronic address: sophia_chai@163.com.
  • Cui L; Institute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China. Electronic address: clisu1@163.com.
  • Zhao X; Institute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China. Electronic address: xzhwd0675@163.com.
  • Zhao X; Institute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China. Electronic address: 1760088942@qq.com.
  • Li B; College of Food Science, Shenyang Agricultural University, Liaoning 110866, China. Electronic address: libinsyau@163.com.
  • Yang Y; Zhejiang Lanmei Technology Co., Ltd, Zhuji 311899, China. Electronic address: yangwj@medelley.com.
  • Huang W; Institute of Agro-Product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China; School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China. Electronic address: wuyanghuang@hotmail.com.
Food Res Int ; 176: 113811, 2024 Jan.
Article en En | MEDLINE | ID: mdl-38163716
ABSTRACT
Blueberries contain an important amount of anthocyanins, which possess numerous biological properties. Nonetheless, the potential applications of anthocyanins may be constrained due to their limited stability and bioavailability. This study aimed to evaluate the stability and absorption of blueberry anthocyanin extracts (BAE) and anthocyanin standards (malvidin and cyanidin glycosides) when encapsulated using ferritin (FR) nanocarriers or a combination of FR and sodium alginate (SA) under simulated gastrointestinal conditions and Caco-2 cell monolayers. These results indicate that the use of FR nanocarriers resulted in an extended-release of anthocyanins during simulated digestion. Particularly, it was observed that after a period of 2 h in the intestinal phase, the anthocyanin concentration in BAE was greater (38.01 µg/mL, P < 0.05) when FR nanocarriers were employed, in comparison to untreated BAE (4.12 µg/mL). Furthermore, outcomes obtained from the Caco-2 cell monolayer assay revealed that FR-anthocyanin encapsulation resulted in substantially higher (P < 0.05) absorption rates ranging from 25.09 to 44.59 % compared to untreated anthocyanins (10.61-22.95 %). These findings provide evidence of an innovative approach for enhancing the stability and bioavailability of blueberry anthocyanins.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Arándanos Azules (Planta) / Antocianinas Límite: Humans Idioma: En Revista: Food Res Int Año: 2024 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Arándanos Azules (Planta) / Antocianinas Límite: Humans Idioma: En Revista: Food Res Int Año: 2024 Tipo del documento: Article