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BET protein-dependent E2F pathway activity confers bell-shaped type resistance to tankyrase inhibitors in APC-mutated colorectal cancer.
Morino, Shun; Mashima, Tetsuo; Shirai, Fumiyuki; Nagayama, Satoshi; Katayama, Ryohei; Seimiya, Hiroyuki.
Afiliación
  • Morino S; Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan.
  • Mashima T; Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Shirai F; Drug Discovery Chemistry Platform Unit, RIKEN Center for Sustainable Resource Science, Wako, Saitama, Japan.
  • Nagayama S; Department of Colorectal Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan; Department of Surgery, Uji-Tokushukai Medical Center, Kyoto, Japan.
  • Katayama R; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan; Division of Experimental Chemotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan.
  • Seimiya H; Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan. Electronic address: hseimiya@jfcr.or.jp.
Cancer Lett ; 584: 216632, 2024 Mar 01.
Article en En | MEDLINE | ID: mdl-38216082
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Poliposis Adenomatosa del Colon / Tanquirasas / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Cancer Lett Año: 2024 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Poliposis Adenomatosa del Colon / Tanquirasas / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Cancer Lett Año: 2024 Tipo del documento: Article País de afiliación: Japón