Emerging applications of single-cell profiling in precision medicine of atherosclerosis.
J Transl Med
; 22(1): 97, 2024 01 23.
Article
en En
| MEDLINE
| ID: mdl-38263066
ABSTRACT
Atherosclerosis is a chronic, progressive, inflammatory disease that occurs in the arterial wall. Despite recent advancements in treatment aimed at improving efficacy and prolonging survival, atherosclerosis remains largely incurable. In this review, we discuss emerging single-cell sequencing techniques and their novel insights into atherosclerosis. We provide examples of single-cell profiling studies that reveal phenotypic characteristics of atherosclerosis plaques, blood, liver, and the intestinal tract. Additionally, we highlight the potential clinical applications of single-cell analysis and propose that combining this approach with other techniques can facilitate early diagnosis and treatment, leading to more accurate medical interventions.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Aterosclerosis
/
Placa Aterosclerótica
Tipo de estudio:
Prognostic_studies
/
Screening_studies
Límite:
Humans
Idioma:
En
Revista:
J Transl Med
Año:
2024
Tipo del documento:
Article
País de afiliación:
China