Impurities in Hyaluronic Acid Dermal Fillers? A Narrative Review on Nonanimal Cross-Linked Fillers.
Facial Plast Surg Aesthet Med
; 26(2): 190-194, 2024.
Article
en En
| MEDLINE
| ID: mdl-38387011
ABSTRACT
Importance Nonanimal cross-linked hyaluronic acid (HA) dermal fillers are among the most versatile tools in minimal invasive esthetic medicine. Filler injections aim to volumize, provide contour, and reduce wrinkles and skinfolds. In the hand of the experienced user, HA fillers have an excellent safety profile. Nevertheless, adverse events have been reported related to poor injection techniques, infection, and immune reactions. Observations In this review, the focus is on filler impurities. Impurities can originate from the fermentation process, crosslinking, packaging, and contamination. Impurities consist of particular and nonparticular matter. We discuss possible risks for the patient to be treated with HA fillers. Conclusions and Relevance Impurities of dermal fillers bear a potential risk for patients, such as delayed autoimmune and inflammatory reactions, biofilm formation, and exposure to leachable Endocrine Disrupting Chemicals. Amount and quality of impurities can be considered as one of the quality parameters of commercially fillers. Considering patient safety, filler impurities should be further reduced.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Envejecimiento de la Piel
/
Técnicas Cosméticas
/
Rellenos Dérmicos
Límite:
Humans
Idioma:
En
Revista:
Facial Plast Surg Aesthet Med
Año:
2024
Tipo del documento:
Article
País de afiliación:
Alemania