The relationship between severe hypertensive diseases of pregnancy and moderate-severe bronchopulmonary dysplasia.
J Perinatol
; 44(7): 935-940, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-38431755
ABSTRACT
OBJECTIVE:
Determine the association between severe hypertensive disease of pregnancy (HDP) with moderate-severe bronchopulmonary dysplasia (BPD) in preterm infants (< 31 weeks' gestation). STUDYDESIGN:
Preterm birth cohort study of 693 mother-infant dyads. Severe HDP was defined as severe preeclampsia, HELLP syndrome or eclampsia. The outcome was moderate-severe BPD classified at 36 weeks corrected gestational age, per the NICHD Consensus statement.RESULTS:
225 (32%) mothers developed severe HDP and 234 (34%) infants had moderate-severe BPD. There was an interaction between severe HDP and gestational age (p = 0.03). Infants born at < 25 weeks gestation to mothers with HDP had increased odds for moderate-severe BPD compared to infants of normotensive mothers delivering at the same gestational age. Infants born > 28 weeks to mothers with severe HDP had decreased odds for the outcome, though not statistically significant.CONCLUSIONS:
Severe HDP has a differential effect on the development of moderate-severe BPD based on gestational age.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Displasia Broncopulmonar
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Recien Nacido Prematuro
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Edad Gestacional
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Hipertensión Inducida en el Embarazo
Límite:
Adult
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Female
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Humans
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Male
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Newborn
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Pregnancy
Idioma:
En
Revista:
J Perinatol
Asunto de la revista:
PERINATOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos