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Broad-spectrum nano-bactericide utilizing antimicrobial peptides and bimetallic Cu-Ag nanoparticles anchored onto multiwalled carbon nanotubes for sustained protection against persistent bacterial pathogens in crops.
Ning, Weimin; Luo, Xiangwen; Zhang, Yu; Tian, Peijie; Xiao, Youlun; Li, Shijun; Yang, Xiao; Li, Fan; Zhang, Deyong; Zhang, Songbai; Liu, Yong.
Afiliación
  • Ning W; Longping branch, Biology College, Hunan University, Changsha 410125, China.
  • Luo X; Key Laboratory of Pest Management of Horticultural Crop of Hunan Province, Hunan Academy of Agricultural Science, Changsha 410125, China.
  • Zhang Y; Key Laboratory of Pest Management of Horticultural Crop of Hunan Province, Hunan Academy of Agricultural Science, Changsha 410125, China.
  • Tian P; Plant Protection College, Yunnan Agricultural University, Kunming 650000, China.
  • Xiao Y; Key Laboratory of Pest Management of Horticultural Crop of Hunan Province, Hunan Academy of Agricultural Science, Changsha 410125, China.
  • Li S; Key Laboratory of Pest Management of Horticultural Crop of Hunan Province, Hunan Academy of Agricultural Science, Changsha 410125, China.
  • Yang X; Longping branch, Biology College, Hunan University, Changsha 410125, China.
  • Li F; Plant Protection College, Yunnan Agricultural University, Kunming 650000, China.
  • Zhang D; Longping branch, Biology College, Hunan University, Changsha 410125, China; Key Laboratory of Pest Management of Horticultural Crop of Hunan Province, Hunan Academy of Agricultural Science, Changsha 410125, China.
  • Zhang S; Longping branch, Biology College, Hunan University, Changsha 410125, China; Key Laboratory of Pest Management of Horticultural Crop of Hunan Province, Hunan Academy of Agricultural Science, Changsha 410125, China. Electronic address: zsongb@hunaas.cn.
  • Liu Y; Longping branch, Biology College, Hunan University, Changsha 410125, China; Key Laboratory of Pest Management of Horticultural Crop of Hunan Province, Hunan Academy of Agricultural Science, Changsha 410125, China. Electronic address: liuyong@hunaas.cn.
Int J Biol Macromol ; 265(Pt 2): 131042, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38521320
ABSTRACT
Worldwide crop yields are threatened by persistent pathogenic bacteria that cause significant damage and jeopardize global food security. Chemical pesticides have shown limited effectiveness in protecting crops from severe yield loss. To address this obstacle, there is a growing need to develop environmentally friendly bactericides with broad-spectrum and sustained protection against persistent crop pathogens. Here, we present a method for preparing a nanocomposite that combines antimicrobial peptides (AMPs) and bimetallic Cu-Ag nanoparticles anchored onto multiwalled carbon nanotubes (MWCNTs). The nanocomposite exhibited dual antibacterial activity by disrupting bacterial cell membranes and splicing nucleic acids. By functionalizing MWCNTs with small AMPs (sAMPs), we achieved enhanced stability and penetration of the nanocomposite, and improved loading capacity of the Cu-Ag nanoparticles. The synthesized MWCNTs&CuNCs@AgNPs@P nanocomposites demonstrated broad-spectrum lethality against both Gram-positive and Gram-negative bacterial pathogens. Glasshouse pot trials confirmed the efficacy of the nanocomposites in protecting rice crops against bacterial leaf blight and tomato crops against bacterial wilt. These findings highlight the excellent antibacterial properties of the MWCNTs&CuNCs@AgNPs@P nanocomposite and its potential to replace chemical pesticides, offering significant advantages for agricultural applications.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Plaguicidas / Nanotubos de Carbono / Nanocompuestos / Nanopartículas del Metal Idioma: En Revista: Int J Biol Macromol Año: 2024 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Plaguicidas / Nanotubos de Carbono / Nanocompuestos / Nanopartículas del Metal Idioma: En Revista: Int J Biol Macromol Año: 2024 Tipo del documento: Article País de afiliación: China