Acute Hepatitis due to Primary Human Immunodeficiency Virus Infection.
Open Forum Infect Dis
; 11(4): ofae170, 2024 Apr.
Article
en En
| MEDLINE
| ID: mdl-38585186
ABSTRACT
The acute retroviral syndrome may present with diverse systemic manifestations and laboratory abnormalities. Here we present a rare case of primary human immunodeficiency virus (HIV) infection causing severe acute hepatitis. Liver histopathology demonstrated a pattern of lymphocytic inflammation consistent with acute hepatitis, high levels of HIV proviral DNA were detected within liver tissue, and immunofluorescence showed HIV p24 antigen within immune and parenchymal cells including hepatocytes. We review the literature pertaining to HIV infection of cell compartments within the liver and discuss the implications for HIV-associated acute liver disease.
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Bases de datos:
MEDLINE
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En
Revista:
Open Forum Infect Dis
Año:
2024
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Article
País de afiliación:
Estados Unidos