Liver Transplantation for Dengue-induced Acute Liver Failure.
J Clin Exp Hepatol
; 14(5): 101405, 2024.
Article
en En
| MEDLINE
| ID: mdl-38660561
ABSTRACT
Although liver involvement has been observed in over two-third cases of dengue viral infection, less than 1% cases progress to dengue-related acute liver failure (D-ALF). Various aspects of management of this disease remain debated including the need and timing of liver transplantation (LT). Moreover, the outcomes of LT for D-ALF have been suboptimal. We present four contrasting cases of D-ALF, two managed with LT and the other two conservatively to highlight the management dilemmas concerning LT in D-ALF. Based on our 4 cases, we would consider dengue shock syndrome, multisystem involvement and neurological deficit not completely accounted for by the ALF as potential contraindications for LT. These would need to be revisited on a case-to-case basis till larger studies define objective selection criteria for LT in D-ALF.
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Bases de datos:
MEDLINE
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En
Revista:
J Clin Exp Hepatol
Año:
2024
Tipo del documento:
Article
País de afiliación:
India