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Skull base surgery for malignant tumors: The 2nd international collaborative study (1995-2015).
Shah, Jatin P; Levyn, Helena; Valero, Cristina; Adilbay, Dauren; Eagan, Alana; Zheng, Junting; Gonen, Mithat; Cohen, Marc; Patel, Snehal; Ganly, Ian; Pai, Prathamesh; Castelnuovo, Paolo; Gao, Fang Ju; Piazza, Cesare; Nicolai, Piero; Panizza, Ben; Bowman, James; Barnett, Catherine; Kowalski, Luiz P; Toledo, Ronaldo; Fliss, Dan M; DeAlmeida, John; Witterick, Ian; Herman, Philippe; Fontanella, Walter; Aniceto, Gregorio Sanchez; Hosal, Sefik; Ozer, Serdar; Iyer, Subramania; Harvey, Richard; Leemans, C Rene; Hendrickx, Jan-Jaap; Figari, Marcelo; Boccalatte, Luis; Nibu, Ken Ichi; Clarke, Peter; Rennie, Catherine; Ming, Zhu Yi; Cernea, Claudio; Goncalves, Sergio; Schlosser, Rodney; Dias, Fernando; Sargi, Zoukaa; Ahmed, Shahzada; Golusinski, Wojciech; Kim, Se Heon; Su, Shirley Y; Raza, Shaan M; DeMonte, Franco; Hanna, Ehab.
Afiliación
  • Shah JP; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Levyn H; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Valero C; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Adilbay D; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Eagan A; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Zheng J; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Gonen M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Cohen M; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Patel S; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Ganly I; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Pai P; Head and Neck Surgical Oncology, Tata Memorial Hospital, Mumbai, India.
  • Castelnuovo P; Department of Otorhinolaryngology, University of Insubria, Varese, Italy.
  • Gao FJ; Department of Head and Neck Surgery, Beijing Tongren Hospital, Beijing, China.
  • Piazza C; Unit of Otorhinolaryngology - Head and Neck Surgery, University of Brescia, Spedali Civili BS Piazzale Spedali Civili, Brescia, Italy.
  • Nicolai P; Unit of Otorhinolaryngology - Head and Neck Surgery, University of Brescia, Spedali Civili BS Piazzale Spedali Civili, Brescia, Italy.
  • Panizza B; Department of Head & Neck Oncology, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.
  • Bowman J; Department of Head & Neck Oncology, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.
  • Barnett C; Department of Head & Neck Oncology, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.
  • Kowalski LP; Head and Neck Reference Center, AC Camargo, Sao Paulo, Brazil.
  • Toledo R; Head and Neck Service, ICESP, São Paulo, Brazil.
  • Fliss DM; Head and Neck Reference Center, AC Camargo, Sao Paulo, Brazil.
  • DeAlmeida J; University of Nicosia Medical School, Cyprus.
  • Witterick I; Department of Otolaryngology - Head & Neck Surgery, University Health Network, Toronto, Ontario, Canada.
  • Herman P; Department of Otolaryngology - Head & Neck Surgery, University Health Network, Toronto, Ontario, Canada.
  • Fontanella W; ENT Department - Skull Base Center, Hispital Lariboisiere APHP, Paris, France.
  • Aniceto GS; Unit of Otorhinolaryngology - Maxillofacial, and Thyroid Surgery, University of Milan, Milan, Italy.
  • Hosal S; Oral and Maxillofacial Department, 12 de Octubre University Hospital, Madrid, Spain.
  • Ozer S; Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Atilim University, Medicana International Ankara, Ankara, Turkey.
  • Iyer S; Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, Atilim University, Medicana International Ankara, Ankara, Turkey.
  • Harvey R; Department of Head and Neck Surgery and Oncology, Amrita Institute of Medical Sciences, Kochi, India.
  • Leemans CR; Sydney Ear Nose Throat Clinic, Darlinghurst, New South Wales, Australia.
  • Hendrickx JJ; Otolaryngology-Head and Neck Surgery, Amsterdam University Medical Center, VU University, Amsterdam, The Netherlands.
  • Figari M; Otolaryngology-Head and Neck Surgery, Amsterdam University Medical Center, VU University, Amsterdam, The Netherlands.
  • Boccalatte L; Head and Neck Surgery, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
  • Nibu KI; Head and Neck Surgery, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
  • Clarke P; Department of Otolaryngology - Head & Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
  • Rennie C; ENT Department, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, United Kingdom.
  • Ming ZY; ENT Department, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, United Kingdom.
  • Cernea C; Head and Neck Surgery, Beijing Cancer Center, Beijing, China.
  • Goncalves S; Head and Neck Service, ICESP, São Paulo, Brazil.
  • Schlosser R; Head and Neck Service, ICESP, São Paulo, Brazil.
  • Dias F; Department of Otolaryngology - Head & Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
  • Sargi Z; Department of Head and Neck Surgery, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
  • Ahmed S; Department of Otolaryngology, University of Miami, Miami, Florida, USA.
  • Golusinski W; Department of Otolaryngology - Head and Neck Surgery, University of Birmingham, University Hospitals Birmingham, Birmingham, United Kingdom.
  • Kim SH; Department of Head and Neck Surgery, The Greater Poland Cancer Centre, Poznan, Poland.
  • Su SY; Department of ENT, Yonsei University Health System, Seoul, South Korea.
  • Raza SM; Department of Head and Neck Surgery, MD Anderson Cancer Center, Houston, Texas, USA.
  • DeMonte F; Department of Neurosurgery, MD Anderson Cancer Center, Houston, Texas, USA.
  • Hanna E; Department of Neurosurgery, MD Anderson Cancer Center, Houston, Texas, USA.
Head Neck ; 2024 May 21.
Article en En | MEDLINE | ID: mdl-38770972
ABSTRACT

BACKGROUND:

The current study presents the effort of a global collaborative group to review the management and outcomes of malignant tumors of the skull base worldwide. PATIENTS AND

METHODS:

A total of 28 institutions contributed data on 3061 patients. Analysis evaluated clinical variables, survival outcomes, and multivariable factors associated with outcomes.

RESULTS:

The median age was 56 years (IQR 44-67). The open surgical approach was used in 55% (n = 1680) of cases, endoscopic resection was performed in 36% (n = 1087), and the combined approach in 9.6% (n = 294). With a median follow-up of 7.1 years, the 5-year OS DSS and RFS were 65%, 71.7% and 53%, respectively. On multivariable analysis, older age, comorbidities, histology, dural/intracranial involvement, positive margins, advanced stage, and primary site were independent prognostic factors for OS, DSS, and RFS. Adjuvant RT was a protective prognostic factor.

CONCLUSION:

The progress across various disciplines may have contributed to improved OS and DSS in this study compared to previous reports.
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Head Neck Asunto de la revista: NEOPLASIAS Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos