Symmetrical structure design of PLGA Biodegradable sinus stents and structure optimization based on surrogate models.
Comput Methods Biomech Biomed Engin
; : 1-10, 2024 May 22.
Article
en En
| MEDLINE
| ID: mdl-38776383
ABSTRACT
This study aims to enhance the degradation uniformity of PLGA sinus stents to minimize fracture risk caused by stress corrosion. Symmetric stent structures were introduced and compared to sinusoidal structure in terms of stress and degradation uniformity during implantation and degradation processes. Three surrogate models were employed to optimize the honeycomb-like structure. Results showed honeycomb-like structures exhibited the superior stress distribution and highest degradation uniformity. The kriging model achieved the smallest error and degradation uniformity of 83.24%. In conclusion, enhancing the symmetry of stent structures improves degradation uniformity, and the kriging model has potential for the optimization of stent structures.
Texto completo:
1
Bases de datos:
MEDLINE
Idioma:
En
Revista:
Comput Methods Biomech Biomed Engin
Asunto de la revista:
ENGENHARIA BIOMEDICA
/
FISIOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
China