Neuromodulation of inhibitory control using phase-lagged transcranial alternating current stimulation.
J Neuroeng Rehabil
; 21(1): 93, 2024 05 30.
Article
en En
| MEDLINE
| ID: mdl-38816860
ABSTRACT
BACKGROUND:
Transcranial alternating current stimulation (tACS) is a prominent non-invasive brain stimulation method for modulating neural oscillations and enhancing human cognitive function. This study aimed to investigate the effects of individualized theta tACS delivered in-phase and out-of-phase between the dorsal anterior cingulate cortex (dACC) and left dorsolateral prefrontal cortex (lDLPFC) during inhibitory control performance.METHODS:
The participants engaged in a Stroop task with phase-lagged theta tACS over individually optimized high-density electrode montages targeting the dACC and lDLPFC. We analyzed task performance, event-related potentials, and prestimulus electroencephalographic theta and alpha power.RESULTS:
We observed significantly reduced reaction times following out-of-phase tACS, accompanied by reduced frontocentral N1 and N2 amplitudes, enhanced parieto-occipital P1 amplitudes, and pronounced frontocentral late sustained potentials. Out-of-phase stimulation also resulted in significantly higher prestimulus frontocentral theta and alpha activity.CONCLUSIONS:
These findings suggest that out-of-phase theta tACS potently modulates top-down inhibitory control, supporting the feasibility of phase-lagged tACS to enhance inhibitory control performance.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Estimulación Transcraneal de Corriente Directa
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Inhibición Psicológica
Límite:
Adult
/
Female
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Humans
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Male
Idioma:
En
Revista:
J Neuroeng Rehabil
/
J. neuroengineering rehabil
/
Journal of neuroengineering and rehabilitation
Asunto de la revista:
ENGENHARIA BIOMEDICA
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NEUROLOGIA
/
REABILITACAO
Año:
2024
Tipo del documento:
Article