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Understanding the Role of Endothelial Cells in Glioblastoma: Mechanisms and Novel Treatments.
Hovis, Gabrielle; Chandra, Neha; Kejriwal, Nidhi; Hsieh, Kaleb Jia-Yi; Chu, Alison; Yang, Isaac; Wadehra, Madhuri.
Afiliación
  • Hovis G; Department of Neurosurgery, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA.
  • Chandra N; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA.
  • Kejriwal N; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA.
  • Hsieh KJ; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA.
  • Chu A; Division of Neonatology and Developmental Biology, Department of Pediatrics, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA.
  • Yang I; Department of Neurosurgery, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA.
  • Wadehra M; Department of Radiation Oncology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA.
Int J Mol Sci ; 25(11)2024 Jun 01.
Article en En | MEDLINE | ID: mdl-38892305
ABSTRACT
Glioblastoma is a highly aggressive neoplasm and the most common primary malignant brain tumor. Endothelial tissue plays a critical role in glioblastoma growth and progression, facilitating angiogenesis, cellular communication, and tumorigenesis. In this review, we present an up-to-date and comprehensive summary of the role of endothelial cells in glioblastomas, along with an overview of recent developments in glioblastoma therapies and tumor endothelial marker identification.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Glioblastoma / Células Endoteliales / Neovascularización Patológica Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Glioblastoma / Células Endoteliales / Neovascularización Patológica Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos