A CASE OF HYPONATREMIA DUE TO PITUITARY METASTASIS OF LUNG CANCER.
Acta Endocrinol (Buchar)
; 19(4): 501-504, 2023.
Article
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| MEDLINE
| ID: mdl-38933238
ABSTRACT
Context Hyponatremia is a common electrolyte abnormality. Objective:
We report a patient who presented with hyponatremia and diagnosed as small cell lung cancer metastatic to hypothalamus and pituitary. Case report A 68 year old male patient was admitted with fever and cough and pneumonia was considered. Serum sodium level was 113 mmol/L. Syndrome of inappropriate ADH (SIADH) is considered. Thyroid function tests and cortisol levels pointed out a central deficiency in both axes. Pituitary MRI was performed and a hypothalamic and pituitary mass were observed. Prednisolone therapy was started followed by L thyroxine replacement. A chest computer tomography (CT) was taken 2 weeks later revealed a mass lesion. Bronchoscopic biopsy was performed and histopathological diagnosis of the tumor was reported as small cell lung cancer.Result:
Many mechanisms were considered as the cause of hyponatremia in our patient. SIADH, secondary adrenal insufficiency and secondary hypothyroidism due to pituitary metastasis are possible causes.Conclusion:
The reason of hyponatremia is sometimes complex. When the underlying causes of hyponatremia are not evaluated in detail, many diagnoses can be missed.
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Bases de datos:
MEDLINE
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En
Revista:
Acta Endocrinol (Buchar)
Año:
2023
Tipo del documento:
Article
País de afiliación:
Turquía