The use of venous blood gas in assessing arterial acid-base and oxygenation status - an analysis of aggregated data from multiple studies evaluating the venous to arterial conversion (v-TAC) method.
Expert Rev Respir Med
; 18(7): 553-559, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-38973767
ABSTRACT
BACKGROUND:
Several methods exist to reduce the number of arterial blood gases (ABGs). One method, Roche v-TAC, has been evaluated in different patient groups. This paper aggregates data from these studies, in different patient categories using common analysis criteria. RESEARCH DESIGN ANDMETHODS:
We included studies evaluating v-TAC based on paired arterial and peripheral venous blood samples. Bland-Altman analysis compared measured and calculated arterial values of pH, PCO2, and PO2. Subgroup analyses were performed for normal, chronic hypercapnia and chronic base excess, acute hyper- and hypocapnia, and acute and chronic base deficits.RESULTS:
811 samples from 12 studies were included. Bias and limits of agreement for measured and calculated values pH 0.001 (-0.029 to 0.031), PCO2 -0.08 (-0.65 to 0.49) kPa, and PO2 0.04 (-1.71 to 1.78) kPa, with similar values for all sub-group analyses.CONCLUSION:
These data suggest that v-TAC analysis may have a role in replacing ABGs, avoiding arterial puncture. Substantial data exist in patients with chronic hypercapnia and chronic base excess, acute hyper- and hypocapnia, and in patients with relatively normal acid-base status, with similar bias and precision across groups and across study data. Limited data exist for patients with acute and chronic base deficits.Palabras clave
Texto completo:
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Bases de datos:
MEDLINE
Asunto principal:
Oxígeno
/
Arterias
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Venas
/
Análisis de los Gases de la Sangre
Límite:
Humans
Idioma:
En
Revista:
Expert Rev Respir Med
Año:
2024
Tipo del documento:
Article
País de afiliación:
Dinamarca